Mediators of Bradykinin-Induced Vasorelaxation in Human Coronary Microarteries
نویسندگان
چکیده
منابع مشابه
Mediators of bradykinin-induced vasorelaxation in human coronary microarteries.
To investigate the mediators of bradykinin-induced vasorelaxation in human coronary microarteries (HCMAs), HCMAs (diameter approximately 300 microm) obtained from 42 heart valve donors (20 men and 22 women; age range, 3 to 65 years; mean age, 46 years) were mounted in Mulvany myographs. In the presence of the cyclooxygenase inhibitor indomethacin, bradykinin relaxed preconstricted HCMAs in a co...
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BACKGROUND Angiotensin (Ang) II type 2 (AT2) receptor stimulation results in coronary vasodilation in the rat heart. In contrast, AT2 receptor-mediated vasodilation could not be observed in large human coronary arteries. We studied Ang II-induced vasodilation of human coronary microarteries (HCMAs). METHODS AND RESULTS HCMAs (diameter, 160 to 500 microm) were obtained from 49 heart valve dono...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2004
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.0000110904.95771.26